Labs that Close the Gap

Laboratory for Innovation Science at Harvard

Researchers at LISH look at the way incentives and governance work in innovation, explore novel approaches to problem-solving and investigate how knowledge is produced and disseminated. LISH’s main partners include the Harvard Medical School, the Broad Institute, NASA, and P&G deploying advanced field-based experiments.


LISH is led by a team of principal investigators from diverse backgrounds: 

  • Karim R. Lakhani, Dorothy and Michael Hintze Professor of Business Administration. He is the founder and co-director of LISH and holds a PHD from MIT. 
  • Eva C. Guinan, Professor, Radiation Oncology, Harvard Medical School. She is the director of the Harvard Catalyst Translational Innovation program. Eva earned her MD from Harvard Medical School.
  • Kyle R. Myers Assistant Professor of Business Administration. He has a PhD from the University of Pennsylvania. He studies the economics of the rate and direction of innovation. 
  • Alberto F. Cavallo, Edgerley Family Associate Professor of Business Administration. Pioneer of measuring inflation, he is the creator of Inflacion Verdadera and co-founder of The Billion Prices and PriceStats. Alberto earned a PhD in Economics from Harvard University.
  • Alexander MacKay, Assistant Professor of Business Administration. He holds a PhD in economics from the University of Chicago.
  • Iavor I. Bojinov, Assistant Professor of Business Administration. He is a Richard Hodgson Fellow and holds a PhD from Harvard University. 
  • Edward McFowland III, Assistant Professor of Business Administration in the Technology and Operations Unit of HBS. Edward holds a PhD from Carnegie Mellon University. 
  • Frank Nagle, Assistant Professor of Business Administration. Frank earned his DBA in Technology and Operations Management from Harvard Business School
  • Jacqueline Ng Lane, Assistant Professor of Business Administration. She holds a PhD from Northwestern University and studies the impact of new technologies on performance outcomes. 

Activities/Research Focus

The Lab focuses on three key areas of investigation:

Open Innovation: 

  • How can organizations use contests, communities, and labor markets to solve complex problems? 
  • How does open innovation transform access to talent? 
  • What does the future of work look like in an era of open talent? 

Science of Science: 

  • What are the drivers, behaviors, and motivation underpinning innovative work? 
  • What makes a successful Lab? 
  • How can science best be applied in solving business challenges?

Data Science and AI: 

  • How is a data-first company built? 
  • What is the role of data science in a firm’s operating model? 
  • How can AI factories be used in organizations? 
  • What impact do algorithms have on the innovation process?

Find out more about LISH here.

The DI is now part of the Digital, Data, and Design (D^3) Institute at Harvard. Read more about this change..